Roles for endocytosis in lentiviral replication
Identifieur interne : 000511 ( Istex/Curation ); précédent : 000510; suivant : 000512Roles for endocytosis in lentiviral replication
Auteurs : Mark Marsh [États-Unis] ; Annegret Pelchen-Matthews [États-Unis] ; James A. Hoxie [États-Unis, Royaume-Uni]Source :
- Trends in Cell Biology [ 0962-8924 ] ; 1997.
English descriptors
- Teeft :
- Amino acids, Biol, Cell biol, Cell biology, Cell surface, Cytoplasmic, Cytoplasmic domain, Endocytic, Endocytic properties, Endocytosis, Endocytosis signal, Endocytosis signals, Endosomes, Envelope glycoprotein, Envelope protein, Glycoprotein, Immunodeficiency, Intracellular vesicles, Late endosomes, Late endosomes lysosomes, Many viruses, Membrane proteins, Mutation, Other aspects, Plasma membrane, Primate lentiviruses, Receptor, Simian immunodeficiency virus, Similar signals, Surface expression, Viral, Viral core complexes, Virion, Virus production.
Abstract
Endocytosis is essential for the entry of many viruses into cells. The primate lentiviruses [human immunodeficiency virus (HIV) 1 and 2, and the simian immunodeficiency viruses (SIVs)], however, use endocytosis in other aspects of their life cycles. Here, the authors describe the ways in which the endocytic pathway is used by HIV and SIV and discuss the mechanisms through which endocytosis may contribute to the pathogenic properties of these viruses.
Url:
DOI: 10.1016/S0962-8924(97)20038-3
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<term>Cytoplasmic</term>
<term>Cytoplasmic domain</term>
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<term>Endocytic properties</term>
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<term>Endocytosis signal</term>
<term>Endocytosis signals</term>
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<term>Envelope glycoprotein</term>
<term>Envelope protein</term>
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<term>Immunodeficiency</term>
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<term>Many viruses</term>
<term>Membrane proteins</term>
<term>Mutation</term>
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<term>Primate lentiviruses</term>
<term>Receptor</term>
<term>Simian immunodeficiency virus</term>
<term>Similar signals</term>
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<front><div type="abstract" xml:lang="en">Endocytosis is essential for the entry of many viruses into cells. The primate lentiviruses [human immunodeficiency virus (HIV) 1 and 2, and the simian immunodeficiency viruses (SIVs)], however, use endocytosis in other aspects of their life cycles. Here, the authors describe the ways in which the endocytic pathway is used by HIV and SIV and discuss the mechanisms through which endocytosis may contribute to the pathogenic properties of these viruses.</div>
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